2-Butanamine

Product Details

CasNo： 13952-84-6

MF： C4H11N

Appearance： liquid

Delivery Time： 15 days

Packing： 200kg/drum

Purity： 99%

Basic Information

• Chinese Name: 仲丁胺（又称一仲丁胺）
• English Name: sec-Butylamine (abbreviated as s-Butylamine)
• CAS No.: 13952-84-6
• Molecular Formula: C₄H₁₁N
• Molecular Weight: 73.14
• Appearance: Colorless liquid
• Odor: Ammonia-like pungent odor

Physical and Chemical Properties

• Melting Point: -104.5℃
• Boiling Point: 62.5℃
• Density: 0.72 g/mL (relative to water, water = 1)
• Relative Vapor Density: 2.52 (relative to air, air = 1)
• Saturated Vapor Pressure: 22.88 kPa (at 25℃)
• Flash Point: -9℃ (closed cup; note: low flash point indicates high flammability)
• Solubility: Soluble in water, ethanol, ether, acetone, and other common organic solvents.

Production Methods

1. High-Pressure Method:

   • Add butanone and Raney nickel catalyst into an autoclave. Conduct hydrogenation and ammoniation reactions three times at 160℃ under a pressure of 3.92-5.88 MPa.
   • After the reaction, cool down and discharge the material, remove waste nickel powder, and add 40% dilute sulfuric acid.
   • Further processes such as steam distillation, vacuum concentration, dehydration, and fractional distillation are performed. The fraction collected at 62-63℃ is the finished sec-butylamine product.

2. Atmospheric Pressure Method:

   • Use butanone as the raw material and Ni-Cr-HPO₃ as the catalyst.
   • Under atmospheric pressure at 115℃, feed the raw materials in a molar ratio of butanone: hydrogen: ammonia = 1:3.5:4.5, and conduct continuous ammoniation-reduction synthesis reaction to produce sec-butylamine. This method has the advantage of mild reaction conditions.

Applications

• Raw Material for Organic Synthesis: Primarily used in the synthesis of pharmaceuticals, dyes, and the herbicide butralin. It acts as a key intermediate to introduce the sec-butylamino group into target molecules.
• Preservative/Fungicide: Approved in China for fruit preservation; it can be used in appropriate amounts according to production needs. The maximum residual limits are specified as follows: ≤0.009 g/kg for lychees, ≤0.005 g/kg for citrus fruits, and ≤0.001 g/kg for apple pulp.
• Other Uses: Also serves as an intermediate in organic synthesis, a chemical reagent for laboratory research, and a fungicide to inhibit the growth of fungi in specific industrial scenarios (e.g., coating preservation).

Safety Information

• GHS Hazard Symbols: GHS02 (Flammable), GHS05 (Corrosive), GHS06 (Toxic), GHS09 (Environmentally Hazardous)
• Hazard Symbol: C (Corrosive)
• Risk Phrases (R-phrases):
  • R11: Highly flammable.
  • R20/22: Harmful by inhalation and if swallowed.
  • R35: Causes severe burns.
  • R50: Very toxic to aquatic organisms.
• Safety Phrases (S-phrases):
  • S16: Keep away from sources of ignition - No smoking.
  • S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • S28: After contact with skin, wash immediately with plenty of soap-suds.
  • S36/37/39: Wear suitable protective clothing, gloves, and eye/face protection.
  • S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
  • S61: Avoid release to the environment. Refer to special instructions/safety data sheets.
  • S9: Keep container in a well-ventilated place.
• Packing Group: II (Medium hazard level for packaging)
• Hazard Class: 3 (Flammable liquids)
• UN Dangerous Goods Shipping Number: UN 2733