Appearance: Colorless liquid with an ammonia-like odor
Odor: Ammonia-like pungent odor
Physical and Chemical Properties
Melting Point: -85℃
Boiling Point: 64-71℃
Density: 0.736 g/mL (at 25℃)
Flash Point: -16℃ (closed cup, typical value)
Solubility: Easily soluble in water; also miscible with organic solvents such as alcohols, ethers, acetone, benzene, and hydrocarbons.
Acidity and Alkalinity: Strongly basic, with a pH value of 12.2 (100 g/L in H₂O, at 20℃)
Production Methods
Ammonolysis of Isobutanol: Isobutanol reacts with ammonia under the action of a catalyst to undergo catalytic dehydration, producing isobutylamine. The ammonolysis of alcohols yields a mixture of primary, secondary, and tertiary amines. By adjusting the ratio of alcohol to ammonia and reaction conditions, the desired proportion of isobutylamine (primary amine) can be obtained.
Reductive Amination of Isobutyraldehyde: Isobutyraldehyde and ammonia undergo catalytic hydrogenation to produce isobutylamine. This method typically yields high-purity primary amine with fewer by-products.
Applications
Organic Synthesis Raw Material: Primarily used in the synthesis of organic compounds such as dyes, plasticizers, and lubricants.
Pesticide Field: Employed in the manufacturing of insecticides (as an intermediate for synthesizing certain pesticide active ingredients).
Other Fields: Also used as a chemical reagent, mineral flotation agent, gasoline anti-knock additive, polymerization catalyst, and stabilizer for specific chemical products.
Safety Information
Toxicity: Toxic. Contact with skin can cause dermatitis and blistering; its vapor may induce symptoms such as headache, thirst, and dryness of the nasal mucosa. Inhalation of high-concentration vapor can irritate the respiratory tract.
UN Dangerous Goods Shipping Number: UN 1214 3/PG 2 (Class 3 Flammable Liquid, Packing Group II)
Protective Measures:
When handling, wear chemical-resistant gloves, safety goggles, and a vapor respirator (or self-contained breathing apparatus in high-concentration environments) to avoid skin and eye contact, as well as vapor inhalation.
Store in a cool, well-ventilated, and fire-proof warehouse, away from oxidizing agents, acids, and open flames.
In case of leakage, isolate the contaminated area, eliminate ignition sources, and use absorbent materials (e.g., vermiculite, sand) to clean up the spill; do not flush directly with large amounts of water to prevent environmental pollution.