N,N-Dimethylacetamide

Product Details

CasNo： 127-19-5

MF： C4H9NO

Appearance： liquid

Delivery Time： 15 days

Packing： 200 kg/drum

Purity： 99%

1. Basic Information

• Molecular Formula: C4H9NO
• Molecular Weight: 87.12 g/mol
• CAS Number: 127 - 19 - 5
• Chemical Name: N,N - Dimethylacetamide
• Alias: DMAC, Dimethylacetoamide

2. Physical Properties

• Appearance: Colorless transparent liquid with a slight amine - like odor.
• Melting Point: -20 °C
• Boiling Point: 165 °C
• Density: 0.943 g/mL (20 °C)
• Flash Point: 66 °C (closed - cup)
• Solubility: Miscible with water, ethanol, ether, acetone, chloroform and other organic solvents. It has strong dissolving ability and can dissolve a variety of organic and inorganic compounds.
• Refractive Index: n??? 1.435 - 1.443

3. Chemical Properties

• Stability: Stable at room temperature, but may decompose under high - temperature or strong - base conditions, releasing toxic nitrogen oxides and carbon monoxide.
• Hydrolysis Reaction: It slowly hydrolyzes under acidic or alkaline conditions to produce acetic acid and dimethylamine.
• Acylation Reaction: It can be used as an acylation reagent in organic synthesis, for example, reacting with halogen - containing hydrocarbons to form amide derivatives.

4. Production Process

• Acetic Acid Method: Acetic acid reacts with dimethylamine in the presence of a catalyst (such as sulfuric acid or ion - exchange resin) to produce dimethylacetamide, which is then purified by distillation.
• Acetyl Chloride Method: Dimethylamine reacts with acetyl chloride, and the by - product is hydrogen chloride. This method has a simple process, but high cost, and is mostly used for laboratory - scale preparation.
• Latest Progress: The use of new catalysts (such as solid acids) and continuous production processes can improve the yield and product purity and reduce environmental pollution.

5. Main Uses

• Solvent: Widely used in synthetic fibers (such as aramid), plastics (such as polyimide), pharmaceutical intermediates, pesticides and other fields. It is an excellent solvent for high - performance polymers.
• Pharmaceutical Industry: As a solvent and reaction medium, it is used in the synthesis of cephalosporin antibiotics, hormonal drugs, etc.
• Electronic Industry: Used in photoresist strippers, electronic cleaning agents, and as a solvent in the manufacturing process of lithium - ion battery electrodes.
• Other Applications: Catalyst carriers, organic synthesis reaction media, coating additives, etc.

6. Quality Standards

• Industrial Grade: Purity ≥99.0%, Moisture ≤0.1%, Colority (APHA) ≤20.
• Electronic Grade: Purity ≥99.9%, Metal Impurities (such as Na, K, Fe) ≤1 ppm, Moisture ≤50 ppm, used for the manufacturing of high - end electronic devices.
• Detection Methods: Gas Chromatography (GC), Karl Fischer Moisture Determination, ICP - MS (Metal Impurity Analysis).

7. Packaging and Storage

• Packaging: Usually packed in iron drums or plastic drums, with a specification of 180 kg/drum or 200 kg/drum.
• Storage Conditions: Store sealed in a cool and ventilated place, away from fire sources and oxidants. When storing for a long time, it is recommended to add a stabilizer to prevent oxidation and decomposition.
• Shelf Life: 12 months (under the specified storage conditions).

8. Safety and Toxicity

• Toxicity: Low - toxicity, LD?? (oral, rat) is about 4.2 g/kg. However, long - term exposure may cause damage to the liver and kidneys, and it is irritating to the skin and eyes.
• Protection Measures: Wear protective gloves, goggles and respirators during operation, and keep good ventilation.
• Emergency Treatment: In case of accidental contact, rinse immediately with a large amount of clean water and seek medical attention.

9. Regulations and Compliance

• Global Regulations: Comply with REACH (EU), TSCA (US) and other chemical registration requirements.
• Transport Classification: Non - hazardous chemicals (UN number: 2810), but it is necessary to comply with the regulations for the transportation of conventional chemicals.