Product Details
CasNo： 102-69-2
MF： C9H21N
Appearance： liquid
Delivery Time： 15 days
Packing： 200kg/drum
Purity： 99%
1. Basic Information
- Chinese Name: 三正丙胺 (Tri-n-propylamine)
- English Name: Tri-n-propylamine
- CAS Number: 102-69-2
- Molecular Formula: C₉H₂₁N
- Molecular Weight: 143.27
- Structural Formula: (CH₃CH₂CH₂)₃N
- Appearance: Colorless transparent liquid with a slight ammonia-like odor, free of mechanical impurities.
2. Physicochemical Properties
- Melting Point: -93.5℃ (Extremely low freezing point; remains liquid in most industrial environments and at room temperature, no anti-freezing treatment required).
- Boiling Point: 156.2℃ (Moderate volatility; easier to store than short-chain tertiary amines (e.g., triethylamine), reducing volatile losses).
- Relative Density: 0.756 g/cm³ (at 20℃; less dense than water. In case of leakage, the liquid floats on water, requiring surface protection).
- Flash Point: 33℃ (closed cup; classified as a "flammable liquid." Although the flash point is higher than that of short-chain amines, it still needs to be kept away from open flames and high temperatures).
- Refractive Index: 1.4190 (at 20℃; stable refractive index, which can be used as an auxiliary indicator to judge product purity).
- Vapor Pressure: 0.47 kPa (at 20℃; low vapor pressure, minimizing the risk of vapor accumulation under normal storage conditions, but ventilation is still necessary).
- Solubility: Slightly soluble in water (solubility ≈ 0.1 g/100 mL at 20℃); fully miscible with most organic solvents such as ethanol, ether, benzene, acetone, and chloroform.
- Stability: Chemically stable and not prone to oxidation or decomposition. However, it is strongly alkaline and reacts rapidly with acids to form salts. Contact with strong oxidizers (e.g., hydrogen peroxide, potassium permanganate) may trigger violent reactions, requiring strict separate storage.
- Explosion Limit: 0.8%–6.0% (by volume). When its vapor mixes with air within this range, it may explode upon contact with ignition sources, so ventilation in the working environment must be controlled.
3. Quality Indicators (Industrial Premium Grade Standard)
| Quality Indicator |
Specification Requirement |
Description |
| Tri-n-propylamine Content |
≥99.0% |
Core active component; high purity prevents impurities from affecting the selectivity and yield of downstream synthesis reactions. |
| Di-n-propylamine Content |
≤0.5% |
Main impurity (secondary amine); excessive content may reduce the purity of pharmaceutical and pesticide intermediates. |
| n-Propylamine Content |
≤0.2% |
Trace impurity (primary amine); strictly controlled to reduce side reactions (e.g., by-product formation in amidation reactions). |
| Water Content |
≤0.1% |
Moisture control prevents product hydrolysis, corrosion of metal packaging, and avoids affecting catalyst activity. |
| Color (Pt-Co Scale) |
≤20 |
Lower color values indicate fewer oxidative impurities (e.g., amine oxides) and stronger storage stability. |
| Other Unknown Impurities |
≤0.3% |
Includes trace high-boiling amines or residual solvents; total content must be strictly limited to meet high-end application requirements. |
4. Main Applications
1. Organic Synthesis Intermediate
- Serves as a tertiary amine catalyst for the curing reactions of polyurethane foams and epoxy resins, regulating reaction rates and improving the mechanical properties of products (e.g., foam elasticity, resin adhesion).
- Synthesizes quaternary ammonium salt compounds (e.g., tri-n-propylbenzylammonium chloride), which are important phase-transfer catalysts widely used in drug synthesis and fine chemical reactions.
2. Pharmaceutical Industry
Used in the synthesis of intermediates for antihistamines and local anesthetics. Its strong alkalinity helps adjust the pH value during reactions, promoting the formation of target products.
3. Pesticide Industry
Acts as an intermediate for synthesizing herbicides and insecticides (e.g., auxiliary raw material for the synthesis of pretilachlor and chlorpyrifos), enhancing the stability and long-term efficacy of pesticides.
4. Surfactants and Additives
- Prepares cationic surfactants, which are used as softeners and antistatic agents in the textile industry, or as rust inhibitors in metalworking fluids.
- Functions as an extreme-pressure anti-wear agent in lubricating oils, reducing wear on metal parts and extending equipment service life.
5. Other Fields
Used as a solvent (for extracting non-polar organic compounds), an additive for stationary phases in gas chromatography analysis, or in the preparation of ion-exchange resins.
5. Packaging, Transportation, and Storage
Packaging
- Industrial Bulk Packaging: 200 L closed galvanized steel drums (inner wall coated with alkali-resistant resin to prevent reaction between metal and amines), with a net weight of 150 kg per drum.
- Small-Batch Packaging: 20 L HDPE plastic drums or 1 L glass reagent bottles (for laboratory R&D or small-scale trial production), with leak-proof gaskets on sealed lids.
Transportation
- Classified as a "flammable liquid" with UN Number: 2376. During transportation, "flammable liquid" and "corrosive" warning signs must be affixed.
- Mixed loading and transportation with strong acids (e.g., sulfuric acid, hydrochloric acid), strong oxidizers, food, and food additives are strictly prohibited. Grounding equipment must be used during loading and unloading to eliminate static electricity, avoiding sparks caused by impact or friction.
Storage
- Store in a cool, dry, and well-ventilated warehouse with a temperature not exceeding 30℃, away from open flames and high-temperature heat sources (e.g., radiators, heating equipment).
- Containers must remain sealed to prevent volatilization and moisture absorption. The storage distance from incompatible substances (oxidizers, acids) should be no less than 10 meters to avoid cross-contamination or hazardous reactions.
6. Safety Precautions
Hazards
- Both the liquid and vapor are irritating. Direct skin contact may cause redness and burns; eye contact can lead to corneal damage. Inhalation of high-concentration vapor irritates the respiratory tract, causing coughing, dizziness, and nausea, and may lead to difficulty breathing in severe cases.
- Flammable; may ignite upon contact with open flames, high temperatures, or static sparks. Toxic gases (e.g., nitrogen oxides) are produced during combustion, requiring anti-toxic protection after fire extinguishing.
Protective Measures
During operation, wear alkali-resistant nitrile gloves, chemical splash goggles, and breathable toxic gas masks (positive-pressure respirators are required if vapor concentration in the environment is high). Explosion-proof ventilation equipment must be installed in the work area to prevent vapor accumulation.
Emergency Handling
- Leakage: Immediately evacuate personnel from the contaminated area and cut off ignition sources. Absorb the leaked liquid with sand or inert adsorbents, collect it for disposal by professional institutions, and do not discharge it directly into sewers or soil.
- Skin Contact: Immediately remove contaminated clothing and rinse the affected area with a large amount of flowing water for at least 15 minutes. Seek medical attention promptly if burns occur.
- Fire: Extinguish fires with dry powder extinguishers or carbon dioxide extinguishers; do not spray water directly (may cause liquid splashing and expand the fire).
