Diisopropylamine

Basic information

  • Product Name:Diisopropylamine
  • CasNo.:108-18-9
  • MF:C6H15N
  • MW:

Physical and Chemical Properties

  • Purity:99%
  • Boiling Point:
  • Packing:liquid
  • Throughput:
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Product Details

CasNo: 108-18-9

MF: C6H15N

Appearance: liquid

Delivery Time: 15 days

Packing: 200kg/drum

Purity: 99%

1. Basic Information

  • Chinese Name: 二异丙胺 (Diisopropylamine)
  • English Name: Diisopropylamine
  • CAS Number: 108-18-9
  • Molecular Formula: C₆H₁₅N
  • Molecular Weight: 101.19
  • Structural Formula: [(CH₃)₂CH]₂NH
  • Appearance: Colorless transparent liquid, with an ammonia-like odor and high volatility.

2. Physicochemical Properties

  • Melting Point: -61℃ (low freezing point, remains liquid in most indoor and industrial environments).
  • Boiling Point: 83–84℃ (moderate volatility; vapor accumulates easily at room temperature if not sealed).
  • Relative Density: 0.7178 g/cm³ (at 20℃; lighter than water, so spilled liquid floats on water surfaces).
  • Flash Point: -6℃ (closed cup; highly flammable—classified as a "flammable liquid." Its vapor can form explosive mixtures with air, posing fire and explosion risks).
  • Solubility: Slightly soluble in water (about 1.4 g/100 mL at 20℃); miscible with most organic solvents, including ethanol, ether, and acetone.
  • Stability: Exhibits strong alkalinity and reacts readily with acids to form salts. It is flammable, and its vapor-air mixtures are explosive. Exposure to high heat or open flames may trigger combustion or explosion. It is incompatible with strong oxidizers (e.g., hydrogen peroxide, potassium permanganate) and halogens.
  • Vapor Density: 3.49 (heavier than air), so vapors tend to settle in low-lying areas (e.g., pits, basement corners), increasing the risk of inhalation and fire.

3. Quality Indicators

Industrial-grade diisopropylamine typically follows strict quality standards, with specifications for premium-grade products as follows:

 

Quality Indicator Specification (Premium Grade) Description
Diisopropylamine Content ≥99.5% Core active component; high purity ensures stable performance in downstream synthesis and avoids impurity interference.
Isopropylamine (Monoisopropylamine) Content ≤0.1% Primary amine impurity; excessive levels reduce reaction selectivity in pharmaceutical and pesticide production.
Water Content ≤0.2% Controls moisture to prevent hydrolysis of amine groups and corrosion of metal storage/transport equipment.
Other Impurities ≤0.2% Includes trace by-products (e.g., triisopropylamine) or residual solvents; strict limits ensure product consistency.
Color (APHA) ≤15 Measures liquid clarity; lower values indicate fewer oxidized impurities and better product purity.

4. Applications

  • Organic Synthesis: Serves as a key intermediate for manufacturing pharmaceuticals, pesticides, and dyes. It acts as a proton acceptor (acid scavenger) in nucleophilic substitution reactions and a catalyst in condensation reactions.
  • Rubber Industry: Used as a raw material for rubber vulcanization accelerators (e.g., thiuram accelerators), which improve rubber’s elasticity, heat resistance, and aging resistance.
  • Pharmaceutical Industry: Critical for producing local anesthetics (e.g., procaine derivatives) and antihistamines, where its alkalinity helps regulate reaction pH and enhance product stability.
  • Pesticide Industry: Synthesizes herbicides (e.g., diuron) and insecticides, contributing to the efficacy and environmental stability of pesticide formulations.
  • Other Fields: Functions as a solvent for extracting non-polar compounds, an emulsifier in coating formulations, an antioxidant for lubricating oils, and a metal preservative (prevents corrosion of iron and steel components).

5. Packaging, Transportation, and Storage

  • Packaging:
    • Industrial packaging: Galvanized steel drums (sealed to prevent volatilization) or tank trucks (equipped with explosion-proof vents and temperature monitors) for bulk transport.
    • Small-volume packaging: Sealed HDPE plastic bottles (1L–20L) or glass containers (for laboratory R&D), with leak-proof caps to avoid vapor escape.
  • Transportation:
    • Classified as a dangerous good (UN number: 1158). During transport, keep away from ignition sources and heat; avoid direct sunlight.
    • Separate from oxidizers, acids, and food chemicals to prevent violent reactions or contamination.
    • Prohibit smoking or open flames near the transport vehicle; use grounded equipment to avoid static electricity during loading/unloading.
  • Storage:
    • Store in a cool, well-ventilated warehouse with a temperature not exceeding 30℃. Keep containers tightly sealed to prevent volatilization and moisture absorption.
    • Store separately from oxidizers and acids (e.g., sulfuric acid, hydrochloric acid); do not mix storage to avoid hazardous reactions.

6. Safety Precautions

  • Hazards: The liquid and vapor are irritating. Skin or eye contact can cause chemical burns; inhalation of high concentrations may irritate the respiratory tract, leading to coughing, dizziness, or shortness of breath.
  • Protective Measures: Wear chemical-resistant gloves, splash-proof goggles, and a gas mask (with amine-specific filters) during operation. Ensure the workplace is well-ventilated.
  • Emergency Handling:
    • Spill response: Evacuate personnel from the contaminated area, isolate the site, and cut off ignition sources. Absorb the spill with inert materials (e.g., sand, vermiculite) or rinse with large amounts of water (for small spills).
    • Fire response: Use dry chemical extinguishers or carbon dioxide extinguishers; avoid water jets, which may spread the flammable liquid and vapor.