Disodium Lauroamphoacetate

Product Details

CasNo： 14350-97-1

MF： C20H37N2O5.HO.2Na

Appearance： liquid

Delivery Time： 15 days

Packing： 25kg/drum

Purity： 99%

1. Basic Information

• English Name: Disodium Lauroamphoacetate; Disodium Lauryl Amphoacetate; DLAA
• Chinese Name: 月桂基两性醋酸钠；月桂基亚氨基二乙酸二钠
• CAS Number: 68603-42-9 (Note: This is a mixture CAS number, as DLAA is derived from lauryl chains and may contain minor homologs; specific grades may have grade-specific identifiers)
• Chemical Structure: C12​H25​N(CH2​COONa)2​ (linear structure, with a 12-carbon lauryl chain as the hydrophobic group and two sodium carboxylate groups as the hydrophilic moieties)
• Average Molecular Weight: Approximately 341.4 g/mol
• Common Synonyms: Lauroamphoacetate Disodium Salt; DLAA; Lauryliminodiacetic Acid Disodium Salt

2. Physical and Chemical Properties

3. Key Performance Characteristics

Ultra-Low Irritation for Sensitive Skin
DLAA’s amphoteric structure minimizes interaction with skin proteins, avoiding over-degreasing or disrupting the skin’s lipid barrier. Skin irritation tests (per OECD 404) rate it ≤0.3 (out of 10), and eye irritation tests (OECD 405) classify it as "tear-free"—making it safe for baby care products, sensitive-skin cleansers, and post-sun care formulations. When compounded with anionic surfactants (e.g., SLES), it reduces irritation by 40%–50% without compromising cleansing power.

Rich, Stable Foaming
It produces fine, dense foam with excellent stability:

• Foam height: ≥140 mm (Ross-Miles foam test, 0.5% aqueous solution at 25°C).
• Foam half-life: >6 minutes (resists collapse in hard water or presence of sebum).
  This foaming profile enhances user experience in cleansers and shampoos, avoiding "weak foam" issues common in other mild surfactants.

1. Strong Compatibility
   DLAA is compatible with all major surfactant types:

• Anionics (SLES, LAS): Reduces their irritation and boosts foam stability.
• Cationics (Polyquaternium-10): No precipitation, enhancing hair conditioning effects in shampoos.
• Nonionics (AEO-3, Cocamide MEA): Improves low-temperature solubility and formulation homogeneity.
  It also works with active ingredients (e.g., hyaluronic acid, niacinamide) and preservatives (e.g., phenoxyethanol, ethylhexylglycerin) without degradation.

1. Mild Conditioning and Moisturizing
   Unlike harsh surfactants, DLAA leaves a temporary moisturizing film on skin and hair:

• On skin: Reduces transepidermal water loss (TEWL) by 18%–22% post-cleansing, avoiding tightness.
• On hair: Coats hair cuticles, reducing friction and improving combability—ideal for tear-free shampoos for children or dry hair formulas.

4. Application Fields & Recommended Dosages

1. Personal Care (Core Scenario)

2. Other Applications

• Dermatological Cleansers: Used in prescription-grade cleansers for eczema or rosacea (10%–20% dosage), as it avoids exacerbating skin inflammation.
• Pet Care Products: Added to mild pet shampoos (8%–15% dosage) for dogs/cats with sensitive skin, preventing dryness or itching.

5. Safety & Usage Guidelines

• Usage Precautions:
  • Dilution: Mix with deionized water at 20–40°C (avoid high temperatures >85°C to prevent degradation). Stir at low speed (300–500 rpm) to avoid excessive foam.
  • Salt Adjustment: Adding small amounts of NaCl (0.5%–2%) can increase viscosity, but avoid over-adding (>5%) as it may cause turbidity.
  • pH Control: Maintain formulation pH between 5.5–7.5 for optimal stability and mildness.
• Safety Protection:
  • Skin Contact: Concentrated DLAA (≥50% active) may cause mild dryness; wear nitrile gloves during handling. Rinse with water if contact occurs.
  • Eye Contact: Flush with plenty of 生理盐水 (normal saline) for 15 minutes if splashed into eyes; seek medical help if irritation persists.
  • Oral Toxicity: Acute oral LD₅₀ (rat) >5,000 mg/kg (low toxicity); do not ingest.
• Regulatory Compliance:
  • Complies with EU CosIng, US FDA (21 CFR), and China’s Cosmetic Safety Technical Specification (2024 Edition).
  • Biodegradable: 28-day biodegradation rate ≥90% (OECD 301B), meeting global environmental standards.

6. Packaging & Storage

1. Packaging Specifications

• Standard Grade (30% active): 25 kg HDPE plastic buckets (with sealed lids and inner liners) or 200 L HDPE drums (for bulk orders).
• High-Active Grade (45%–50% active): 20 L HDPE plastic buckets (to reduce transportation costs for concentrated formulations).
• Sample Sizes: 100 mL/500 mL HDPE bottles (for R&D and small-batch testing).

2. Storage Conditions

• Store in a cool, dry, well-ventilated warehouse (temperature 5–35°C, relative humidity <75%); avoid direct sunlight and high temperatures (>40°C).
• Keep sealed after opening to prevent moisture absorption or microbial contamination.
• Shelf Life: 24 months for unopened packages; use opened packages within 3 months.