Disodium Cocoamphoacetate

Basic information

  • Product Name:Disodium Cocoamphoacetate
  • CasNo.:68650-39-5
  • MF:
  • MW:

Physical and Chemical Properties

  • Purity:99%
  • Boiling Point:
  • Packing:liquid
  • Throughput:
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Product Details

CasNo: 68650-39-5

Appearance: liquid

Delivery Time: 15 days

Packing: 200kg/drum

Purity: 99%

1. Basic Information

  • English Name: Disodium Cocoamphoacetate; Disodium Cocoyl Amphoacetate; DCAA
  • Chinese Name: 椰油酰胺丙基甜菜碱乙酸二钠;椰油两性乙酸二钠
  • CAS Number: 68603-42-9 (mixture CAS number, as it consists of derivatives from coconut oil fatty acids with varying chain lengths, mainly C12-C18)
  • Chemical StructureRCONHCH2​CH2​CH2​N+(CH3​)2​CH2​COONa+ (where R represents the cocoalkyl group, i.e., C12-C18 alkyl chains, with C12-C14 as the predominant average)
  • Average Molecular Weight: Approximately 420–480 g/mol (varies slightly based on the distribution of cocoalkyl chain lengths)
  • Common Synonyms: Disodium Cocoamphodiacetate; Cocoamphoacetate Disodium Salt; DCAA

2. Physical and Chemical Properties

Indicator

Typical Value (Cosmetic Grade, 30% Active Aqueous Solution)

Description

Appearance

Colorless to pale yellow transparent liquid

May appear slightly turbid at low temperatures (<5°C); reverts to transparency when warmed (>15°C), with no impact on performance.

Active Content

28.0%–32.0% (common commercial concentration); 50% high-active versions also available

High-active grades require dilution based on formulation needs.

pH Value (1% aqueous solution, 25°C)

6.0–8.0

Near-neutral, compatible with the pH range of most personal care products, avoiding skin irritation or formulation instability.

Viscosity (25°C, mPa·s)

500–3000

Low viscosity facilitates mixing with other raw materials, eliminating the need for additional viscosity reducers.

Density (25°C, g/cm³)

1.03–1.08

Stable density enables accurate dosage measurement in industrial production.

Solubility

Easily soluble in water; miscible with polar solvents (e.g., ethanol, propylene glycol); insoluble in non-polar solvents (e.g., mineral oil, silicone oil)

Suitable for water-based cleansing/care formulations; nonionic emulsifiers are required if oil-phase emulsification is needed.

Stability

Stable to acids (pH 4–10) and hard water (calcium/magnesium ion concentration <500 ppm); may undergo slow hydrolysis under strong alkaline conditions (>pH 12) or high temperatures (>80°C); compatible with oxidizing agents (e.g., sodium hypochlorite)

Stable under typical cosmetic production and usage conditions, no additional stabilizers required.

3. Key Performance Characteristics

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Extreme Gentleness with Low Irritation and Non-Sensitization
As an amphoteric surfactant, its molecular charge adjusts adaptively with pH, avoiding excessive degreasing of the skin’s stratum corneum or protein denaturation. It scores ≤0.2 (out of 10) in skin irritation tests (per OECD 404 standard) and is rated "non-irritating" in eye irritation tests (OECD 405 standard). Additionally, it passes allergen screening under the EU EC 1223/2009 Cosmetics Regulation (free of fragrances, preservatives, and other additional sensitizing ingredients), making it suitable for strict scenarios such as baby body washes, sensitive-skin cleansers, and pregnancy care products.

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Balanced Cleansing and Moisturization, No Tightness
Compared to traditional anionic surfactants (e.g., SLES, LAS), DCAA forms a temporary moisturizing film on the skin while cleansing oil and dirt, reducing transepidermal water loss (TEWL) by over 20%. Skin moisture content increases by 15%–20% after use, avoiding the "tightness" caused by ordinary cleansing products—especially suitable for dry and sensitive skin types.

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Fine and Stable Foam, Strong Synergistic Effects
When used alone, it produces fine, dense foam (foam height ≥150 mm via Ross-Miles foam test) with a half-life of over 5 minutes. When compounded with other surfactants, it exhibits "synergistic effects":

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  • Compounded with SLES (1:2 mass ratio): Reduces SLES irritation by 40% while tripling foam stability.
  • Compounded with cationic conditioners (e.g., Polyquaternium-73): No precipitation risk; also enhances hair smoothness and reduces frizz.
  • Compounded with nonionic surfactants (e.g., AEO-3): Further improves low-temperature solubility, suitable for cold-water 洗护 (cleansing/care) products.

 

  1. Excellent Compatibility, Wide Formulation Adaptability
    It has good compatibility with anionic, cationic, nonionic, and other amphoteric surfactants, with no precipitation, stratification, or discoloration. It also does not damage preservatives (e.g., phenoxyethanol, hexanediol) or active ingredients (e.g., panthenol, hyaluronic acid, niacinamide), making it flexible for use in various cosmetic formulations such as cleansers, body washes, shampoos, and hand soaps—no complex compatibility testing required.

4. Application Fields

1. Personal Care (Core Scenario)

  • Sensitive-Skin/Baby Care Products:
    • Baby 2-in-1 body wash/shampoo: Used as the main surfactant (15%–25% addition), compounded with Cocamidopropyl Betaine (CAPB, 5%–10%) to achieve "cleansing + moisturizing + low irritation" triple effects, meeting EU ECOCERT organic certification standards.
    • Sensitive-skin cleansers: Added at 20%–30%, replacing traditional soap bases or SLES to avoid damage to the skin barrier caused by over-cleansing—suitable for acne-prone and rosacea-prone skin.
  • Adult Care Products:
    • Mild body washes: Added at 10%–20%, compounded with plant extracts (e.g., oat kernel extract, chamomile extract) to enhance moisturizing and soothing effects, suitable for dry seasons or dry skin.
    • Silicone-free shampoos: Used as an auxiliary surfactant (8%–15%) to reduce scalp irritation from main surfactants (e.g., SLES) while improving hair combability.
    • Hand soaps: Added at 12%–18%, especially suitable for medical hand soaps and children’s hand soaps—balancing cleansing power and gentleness, without damaging the hand skin barrier with long-term use.

2. Household Cleaning

  • Baby-Specific Cleaners: Used in baby laundry detergents and bottle cleaners (5%–10% addition) to gently remove milk stains and baby food residues, with easy rinsing and no residue—avoiding skin irritation from chemical substances.
  • Sensitive-Skin Laundry Detergents: Added at 8%–12%, replacing part of LAS to reduce irritation from post-washing residue on clothes, suitable for cleaning intimate apparel.

3. Other Special Fields

  • Medical Cleaning Products: Used as a surfactant in medical hand soaps and around-wound cleansers (10%–15% addition)—providing gentle cleansing without damaging the skin’s antibacterial barrier, meeting medical-grade cleaning standards.
  • Pet Care Products: Used in pet body washes for cats, dogs, etc. (12%–20% addition), avoiding dandruff and itching caused by irritating surfactants on pet skin—especially suitable for pets with sensitive skin.

5. Safety & Usage Guidelines

  • Usage and Handling:
    • Dilution Method: Add DCAA slowly to deionized water at 20–40°C, stirring while adding (stirring speed 300–500 rpm) to avoid foam overflow from local high concentration. If mixing with high-concentration acids/alkalis, first dilute the acid/alkali to below 5%, then slowly add to the DCAA solution to prevent hydrolysis caused by sudden pH changes.
    • Recommended Dosage: 15%–30% as the main surfactant, 5%–15% as the auxiliary surfactant. Adjust based on cleansing power and gentleness requirements (≥20% recommended for baby products, as low as 10% for adult cleansing products).
  • Safety Protection:
    • Skin Contact: Although gentle, long-term contact with high-active (50%) versions may cause slight dryness; wear nitrile gloves during handling. Rinse with water if contact occurs.
    • Eye Contact: If splashed into eyes, immediately rinse with plenty of normal saline for 15 minutes; seek medical attention if necessary.
    • Oral Toxicity: Acute oral LD₅₀ (rat) >5000 mg/kg (low toxicity). If ingested, induce vomiting immediately and seek medical help.
  • Environmental & Regulatory Compliance:
    • Biodegradability: Meets EU OECD 301B standards, with 28-day biodegradation rate ≥90%—classified as an "easily biodegradable" surfactant, with no cumulative harm to aquatic environments.
    • Regulatory Compliance: Complies with EU CosIng, US FDA (21 CFR), and China’s Cosmetic Safety Technical Specification (2024 Edition), with no prohibited or restricted ingredients—suitable for global sales.

6. Packaging & Storage

1. Packaging Specifications

  • Cosmetic Grade (30% Active): 200 L HDPE food-grade plastic drums (net weight 200 kg/drum), 1000 L IBC totes (net weight 1000 kg/tote). Drum mouths are equipped with sealed lids + inner plugs to prevent leakage and microbial contamination.
  • High-Active Grade (50% Active): 25 L HDPE plastic drums (net weight 25 kg/drum), suitable for small-batch formulation R&D.
  • Sample Sizes: 100 mL/500 mL HDPE small bottles, for customer formulation testing and trials.

2. Storage Conditions

  • Store in a cool, dry, well-ventilated warehouse (temperature 5–35°C, relative humidity <75%); avoid direct sunlight and high temperatures (>40°C) to prevent active ingredient hydrolysis or microbial growth.
  • Keep moisture-proof and sealed: Seal immediately after opening, and tighten the drum lid promptly after each use. For long-term storage, test pH and viscosity monthly to ensure stable performance.
  • Shelf Life: 24 months when unopened, stored in a dark and sealed environment; use opened packages within 3 months.