Poly (N-Vinylpyrrolidone-co-2-Dimethylaminoethyl Methacrylate) Diethyl Sulfate

Basic information

  • Product Name:Poly (N-Vinylpyrrolidone-co-2-Dimethylaminoethyl Methacrylate) Diethyl Sulfate
  • CasNo.:53633-54-8
  • MF:(C8H15NO2)x.(C6H9NO)y.(C4H10O4S)z
  • MW:

Physical and Chemical Properties

  • Purity:99%
  • Boiling Point:
  • Packing:liquid
  • Throughput:
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Product Details

CasNo: 53633-54-8

MF: (C8H15NO2)x.(C6H9NO)y.(C4H10O4S)z

Appearance: liquid

Delivery Time: 15 days

Packing: 200kg/drum

Purity: 99%

1. Basic Information

  • Chinese Name: 聚(N - 乙烯基吡咯烷酮 - co - 甲基丙烯酸二甲氨基乙酯)硫酸二乙酯盐
  • English Name: Poly (N-Vinylpyrrolidone-co-2-Dimethylaminoethyl Methacrylate) Diethyl Sulfate
  • Abbreviation: PVP-co-DMAEMA Diethyl Sulfate; Quaternized PVP/DMAEMA Copolymer
  • CAS Number: 53633-54-8
  • Molecular Formula: (C8​H15​NO2​)x​⋅(C6​H9​NO)y​⋅(C4​H10​O4​S)z​ (where x,y,z represent the repeating unit counts of DMAEMA, PVP, and diethyl sulfate quaternary groups, respectively)
  • Average Molecular Weight: Typical range of 50,000–500,000 Da, customizable by application:
    • Low molecular weight (50k–100k Da): Suitable for hair styling sprays (enhanced spreadability).
    • Medium molecular weight (100k–300k Da): Ideal for hair conditioners and skin care creams.
    • High molecular weight (300k–500k Da): Used in industrial anti-static coatings (superior film adhesion).
  • Common Synonyms: Quaternized PVP-co-DMAEMA; PVP/DMAEMA copolymer diethyl sulfate salt; Cationic polyvinylpyrrolidone copolymer

2. Physical and Chemical Properties

Indicator

Typical Value (Industrial/Cosmetic Grade)

Description

Appearance

Colorless to pale yellow transparent viscous liquid (30%–50% solid content) or white to off-white powder (≥95% solid content)

No visible impurities, ensuring no discoloration of end products.

Solid Content

30%–50% (liquid grade); ≥95% (solid grade)

Liquid grade enables direct formulation; solid grade reduces storage/transport costs.

Molar Ratio (PVP:DMAEMA)

30:70 to 70:30 (customizable)

Higher PVP ratio enhances film flexibility; higher DMAEMA ratio boosts cationic charge density.

Quaternization Degree

≥95%

High quaternization ensures strong electrostatic adsorption (charge density: 1.5–3.0 meq/g) on negatively charged surfaces (e.g., hair cuticles).

pH Value (1% aqueous solution, 25°C)

5.5–7.5

Near-neutral, matching the pH range of human skin (4.5–6.5) and hair, avoiding irritation.

Viscosity (25°C, Brookfield; 30% liquid grade)

500–5,000 mPa·s

Viscosity tailored to product type: Low viscosity for sprays; high viscosity for creams.

Solubility

Easily soluble in water, ethanol, propylene glycol, and other polar solvents; insoluble in non-polar solvents (e.g., hexane, benzene)

Universal solubility simplifies blending in multi-solvent cosmetic/pharmaceutical formulations.

Thermal Stability

Decomposition temperature ≥200°C; stable for 6 months at 50°C (liquid grade)

Resists degradation during high-temperature processing (e.g., cosmetic emulsion homogenization).

Hygroscopicity

Low (solid grade: absorbs ≤5% moisture at 60% RH, 25°C)

Prevents caking in storage and maintains stability in humid environments.

3. Key Performance Characteristics

  1. Dual Functional Synergy: Cationic Conditioning + Flexible Film-Forming
    The quaternized DMAEMA segment delivers strong cationic charge, enabling rapid adsorption on negatively charged hair/skin surfaces to form a protective layer that reduces static and frizz. The PVP segment provides a soft, water-resistant film—unlike rigid cationic polymers, it avoids hair stiffness, keeping styles natural and skin smooth without tightness.
  2. Excellent Compatibility and Formulation Versatility
    Compatible with anionic (e.g., SLES), non-ionic (e.g., cocamide DEA), and amphoteric (e.g., CAPB) surfactants, as well as active ingredients (e.g., vitamins, plant extracts) and preservatives. It does not cause precipitation or phase separation, and even enhances the stability of emulsions by reducing particle aggregation.
  3. Superior Biocompatibility and Safety
    Derived from FDA-approved PVP, it exhibits low skin irritation (human patch test: "non-irritating") and no sensitization. It is non-toxic (oral LD₅₀ > 10,000 mg/kg in rats), making it safe for sensitive skin, baby care products, and pharmaceutical applications.
  4. Durable Performance and Environmental Resistance
    On hair, its film retains styling through high humidity (80% RH for 24 hours) without flaking. In coatings, it adheres tightly to substrates (e.g., metal, plastic) and resists mild chemicals (e.g., shampoo surfactants), ensuring long-lasting anti-static or protective effects.

4. Application Fields

1. Personal Care (Core Scenario)

  • Hair Care Products:
    • Hair Styling: Hairsprays, mousses, and gels—provides long-lasting hold (8+ hours) with natural flexibility, avoiding hair brittleness.
    • Hair Conditioners: Adsorbs on damaged hair cuticles, filling gaps to reduce split ends and improve combability; enhances hair shine without weighing it down.
    • Anti-Dandruff Shampoos: Binds to scalp and hair, prolonging the retention of anti-dandruff actives (e.g., zinc pyrithione) and reducing dandruff recurrence.
  • Skin Care Products:
    • Moisturizers/Serums: Forms a breathable film on skin to lock in moisture (reduces transepidermal water loss by 20%) while allowing skin respiration.
    • Shaving Products: Reduces friction between razor and skin, preventing irritation; leaves a smooth post-shave finish.
    • Liquid Soaps/Bath Gels: Improves skin feel, reducing dryness caused by surfactants.

2. Pharmaceutical Industry

  • Oral Solid Dosages: Film coating for tablets/capsules—masks drug bitterness, improves swallowing, and dissolves rapidly in the gastrointestinal tract.
  • Topical Formulations: Wound care creams/ointments—acts as a protective film to prevent contamination and promote moist healing.

3. Industrial Applications

  • Anti-Static Coatings: Used in electronic components, plastic films, and textile fibers—lowers surface resistance to <10⁹ Ω/sq, preventing static buildup that damages electronics or attracts dust.
  • Adhesives: Enhances adhesion of pressure-sensitive adhesives to polar substrates (e.g., plastic labels) and improves resistance to humidity.

5. Safety Information

  • Cosmetic/Pharmaceutical Grade Safety: Complies with FDA, EU CosIng, and China NMPA standards. No reports of acute/chronic toxicity; safe for daily use in cosmetics (typical addition: 0.1%–2%) and pharmaceuticals.
  • Industrial Grade Safety: Low irritation to skin/eyes; wear gloves and goggles during handling. Avoid mixing with strong oxidants (e.g., hydrogen peroxide) to prevent polymer degradation.
  • Environmental Safety: Biodegradable (degradation rate > 60% per EU EC 1272/2008); non-toxic to aquatic organisms (fish LC₅₀ > 1,000 mg/L), meeting global green chemistry requirements.

6. Packaging and Storage

1. Packaging Forms

  • Liquid Grade: 200L HDPE plastic drums (with sealed liners) or 1,000L IBC totes—leak-proof, suitable for bulk transportation.
  • Solid Grade (Powder): 25kg kraft paper bags (lined with PE film) or 50kg cardboard drums—moisture-proof, preventing caking.
  • Sample Sizes: 1L/5L HDPE bottles (liquid) or 1kg/5kg aluminum foil bags (solid)—for R&D or small-batch trials.

2. Storage Conditions

  • Store in a cool, dry, well-ventilated area (temperature: 5–35°C, relative humidity: <75%); avoid direct sunlight and high temperatures (>40°C) to prevent viscosity changes or degradation.
  • Liquid grade: Avoid long-term static storage; gently invert drums monthly to ensure uniform concentration.
  • Shelf Life: Unopened liquid grade: 18 months; unopened solid grade: 24 months. Use opened products within 3 months and reseal promptly.