Product Details

CasNo： 604-69-3

MF： C16H22O11

Appearance： powder

Delivery Time： 15 days

Packing： 25kg/drum

Purity： 99%

Basic Information

Product Description

Product Name：β -pentaacetylglucose

CAS No: 604-69-3

Form:powder

Product Application

1 Pharmaceutical Synthesis (Core Application)

β-Pentaacetyl glucose is an irreplaceable intermediate for constructing β-glycosidic bond drugs, especially in:

Nucleotide Drug Synthesis: For β-configured nucleotide analogs like tenofovir and adefovir—after deprotecting the C₁ acetyl group, it couples with phosphate or other functional groups to form β-glycosidic bonds (natural nucleotides are predominantly β-configured).

Oligosaccharide/Polysaccharide Synthesis: Mimics natural polysaccharide β-glycosidic bonds (e.g., cellulose, starch) to synthesize functional oligosaccharides (e.g., heparin, chondroitin sulfate) for pharmaceuticals (intermediates or targeted drug carriers).

Antibiotic Synthesis: Introduces β-glycosidic structures in macrolide antibiotics (e.g., erythromycin, vancomycin) via β-pentaacetyl glucose.

2 Glycoscience Research

β-Glycosylation Template: Acts as a β-configured glycosyl donor, undergoing β-selective glycosylation with acceptors (e.g., alcohols, amines, thiols) under Lewis acid catalysis (e.g., BF₃·Et₂O, TMSOTf) to study glycosidic bond formation mechanisms and stereoselectivity control.

Configurational Analysis Standard: Used as a reference for β-D-glucose derivatives in HPLC, NMR, and other analytical methods to distinguish α/β isomers.

3 Materials Science

Biodegradable Materials: Polymerizes via β-glycosidic bonds to produce β-glucan derivatives for drug delivery carriers, tissue engineering scaffolds, etc.

Functional Coatings: Leverages the steric hindrance of β-configuration to prepare surfaces with unique wettability or biocompatibility.

Packaging

25kg/drum

Storage

Store in a cool, dry, dark place (temperature ≤25°C, relative humidity ≤60%).