Sodium L-ascorbyl-2-phosphate

Product Details

CasNo： 66170-10-3

MF： C6H6Na3O9P

Appearance： powder

Delivery Time： 15 days

Packing： 25kg/bag

Purity： 99%

1. Basic Information

• Chinese Name: 维生素 C 磷酸酯钠
• English Name: Sodium Ascorbyl Phosphate (SAP)
• INCI Name: Sodium Ascorbyl Phosphate
• CAS Number: 66170-10-3
• Molecular Formula: C6​H6​Na3​O9​P
• Molecular Weight: 322.06
• Chemical Structure: The 2-position hydroxyl group of vitamin C (ascorbic acid) is replaced by a phosphate group to form a sodium salt. Its molecular structure is stable and not easily oxidized.

2. Physicochemical Properties

• Appearance: White to off-white crystalline powder, odorless or slightly having a special odor.
• Solubility: Easily soluble in water (solubility about 100g/L at 25℃), slightly soluble in ethanol and propylene glycol, insoluble in organic solvents such as chloroform and ether, and easily dispersible in cosmetic formulations.
• Stability: Compared with native vitamin C (ascorbic acid), its stability is significantly improved. It is resistant to high temperatures (below 60℃) and light, and not easy to discolor or decompose within the pH range of 4.0-7.0 (suitable for most cosmetic systems). Avoid contact with strong oxidants and heavy metal ions (e.g., Fe³⁺, Cu²⁺).
• pH Value: The pH of a 1% aqueous solution is 6.0-7.5, showing weak neutrality, with low skin irritation (avoiding the acidic irritation of native vitamin C).

3. Quality Indicators

As a precursor of vitamin C, sodium ascorbyl phosphate releases active vitamin C (ascorbic acid) under the action of phosphatase in the skin, thereby exerting its effects:4. Mechanism of Action

• Whitening and Spot-Lightening: Inhibits the activity of tyrosinase (a key enzyme in melanin synthesis), blocks the conversion of dopa to dopaquinone, reduces melanin production, and promotes the metabolism of formed melanin to lighten spots and brighten skin tone.
• Antioxidant Protection: Scavenges free radicals (e.g., ROS) in the skin, reduces oxidative damage to the skin caused by external stimuli such as ultraviolet rays and pollution, delays collagen loss, and improves skin roughness and fine lines.
• Barrier Repair: Promotes the synthesis of lipids in the skin stratum corneum, enhances the skin barrier function, improves the skin's water retention capacity, and relieves dryness and sensitivity.

5. Applications

• Cosmetics Industry: Core application in whitening and anti-aging products, such as serums, lotions, creams, masks, and foundations. The recommended addition amount is 0.5%-3.0%. Due to its high stability and low irritation, it is also suitable for sensitive skin and baby skincare products.
• Food Industry: Used as a nutritional fortifier (to supplement vitamin C) in fruit juices, beverages, dairy products, baked goods, etc. Meanwhile, it acts as an antioxidant to delay food oxidation and deterioration (e.g., preventing browning of fruits and vegetables). The maximum usage amount shall comply with GB 2760 National Food Safety Standard for the Use of Food Additives.
• Pharmaceutical Industry: Applied in oral care products (e.g., toothpaste, to prevent gum bleeding and improve oral mucosa health) or as an ingredient in topical preparations (to assist in the treatment of skin inflammation and promote wound healing).

6. Packaging & Storage

• Packaging: The inner layer is a food-grade polyethylene plastic bag, and the outer layer is an aluminum foil bag or cardboard drum. Available specifications include 1kg/bag, 5kg/bag, and 25kg/drum (custom small-batch packaging is available).
• Storage: Seal and store in a cool, dry place (temperature ≤30℃, relative humidity ≤60%), away from light and moisture. Avoid mixing and storing with strong oxidants and heavy metal compounds.
• Shelf Life: Under unopened condition and proper storage, the shelf life is 24 months.