HEPARIN LITHIUM SALT

Product Details

CasNo： 9045-22-1

Appearance： 白色结晶固体

Delivery Time： 15 days

Packing： 25kg/drum

Purity： 90%

• Basic Information
  • English Name: Heparin lithium; Heparin lithium salt
  • CAS Number: 9045 - 22 - 1
  • Appearance: White or off - white amorphous powder.
  • Grade: Usually BR (Biological Reagent).
  • Molecular Weight: 6000 - 15000
• Specifications and Packaging
  • Specifications: The potency is ≥150IU/mg. There are also products with a potency of approximately 200 units/mg.
  • Packaging: It can be packaged in 1kg aluminum - foil bags (domestic) or 1kg aluminum cans (export). There are also small - package products, such as 250mg packaged in 5ml amber glass vials.
• Anticoagulation Principle
  • Heparin lithium binds reversibly to antithrombin III (AT - III). It significantly inhibits exosome - cell interactions. Heparin lithium is believed to function as an anticoagulant primarily through its interaction with AT - III, enhancing AT - III - mediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin binds to AT - III and thrombin in a ternary complex, increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000.
• Product Advantages
  • Low Interference: Heparin lithium is the most recommended form of heparin because of its low interference level with tests of other ions. It is essentially free of extraneous ions, and it should not be used for testing lithium in blood. For electrolyte testing, heparin lithium has shown a higher level of accuracy in the tests than sodium heparin and ammonium heparin.
  • Widely Used in Clinical Biochemistry: Heparin is a commonly used anticoagulant, especially in clinical biochemistry and chemical measurement tests. It is the recommended anticoagulant for chemical measurement in blood or plasma tests, because of its minimal chelating properties, minimal interference with water, and relatively low cation concentration. Heparin is the anticoagulant of choice for measuring pH, blood gases, electrolytes, and ionized calcium.
• Precautions for Use
  • Avoid Mixing with Other Anticoagulants: Heparin lithium should not be mixed with other anticoagulants, as this may lead to abnormal anticoagulation effects and affect the accuracy of test results.
  • Pay Attention to Storage Conditions: It should be stored in a cool, dry place, protected from light. The storage temperature is usually 2 - 8°C.
  • Standardize the Operation Process: When using it, ensure that the heparin lithium in the blood collection tube is evenly distributed. After collecting the blood sample, immediately invert the blood collection tube gently 5 - 8 times to fully mix the blood with heparin lithium, but avoid 剧烈 shaking to prevent damage to blood cells.