Uricase

Product Details

CasNo： 9002-12-4

MF： C18H26N5O14P

Appearance： powder

Delivery Time： 15 days

Packing： 25kg/drum

Purity： 99%

• Basic Information
  • English Name: Uricase
  • CAS No.：9002-12-4
  • Alias：Urate oxidase
  • Appearance：White powder
  • Molecular Weight：Approx. 34kDa
  • Isoelectric Point：5.4
• Physical and Chemical Properties
  • Enzyme Activity：The specific activity of biotechnology - grade uricase is ≥10U/mg protein. One unit of enzyme activity is defined as the amount of enzyme required to oxidize 1 micromole of uric acid per minute at pH 8.5 and 25℃.
  • Optimum pH：8.5
  • Optimum Temperature：37℃
  • pH Stability：Stable in the range of pH 6.0 - 11.0 (25℃, 20 hours)
  • Thermal Stability：Stable below 65℃ (pH 8.5, 10 minutes)
  • Inhibitors：Metal ions such as Ag+, Hg2+, Cu2+, Zn2+, Fe3+, Ni2+, Co2+ can inhibit its activity.
• Storage Conditions：Store at - 20℃.
• Usage：Uricase can decompose uric acid into allantoin. Allantoin has a higher solubility and is easy to be excreted from the body. Therefore, uricase helps to reduce the uric acid level in the body and can be used for the clinical detection and treatment of uric - acid - related diseases, such as gout, kidney disease, cardiovascular disease, etc.