Tris Base

Product Details

CasNo： 77-86-1

MF： C4H11NO3

Appearance： White Powder

Delivery Time： 15 days

Packing： 25kg/bag

Purity： 99%

• Basic Information
  • Chinese Name: Tris - (hydroxymethyl)aminomethane, also known as trometamol, tris(hydroxymethyl)aminomethane, Tris base, THAM.
  • English Name: Tris(hydroxymethyl)aminomethane, abbreviated as Tris.
  • CAS No. : 77 - 86 - 1.
  • Molecular Formula : C₄H₁₁NO₃.
  • Molecular Weight : 121.14.
• Physical and Chemical Properties
  • Appearance: White crystalline particles or white to light yellow crystalline powder.
  • Melting Point: 168 - 172℃.
  • Boiling Point: 219 - 220℃/13.3 hPa.
  • Density: 1.32 g/cm³ at 20℃.
  • Solubility: Easily soluble in water with a solubility of 678 g/L, slightly soluble in ethanol, insoluble in organic solvents such as diethyl ether.
  • Acidity and Alkalinity: Tris - (hydroxymethyl)aminomethane is a weak base. At 25°C, its pKa is 8.1, and the pH of its aqueous solution is about 10.5.
• Usesthermofisher.com
  • Biological Buffer: Widely used as a solvent for nucleic acids and proteins, used for the growth of protein crystals under different pH conditions, and is also one of the main components of protein electrophoresis buffer. It forms a buffer system with glycine in the electrophoresis buffer to stabilize the pH during the electrophoresis process.
  • Medical Field: As an alkaline drug, it is used for the correction of acidosis without causing an increase in carbon dioxide retention. It is also an intermediate of drugs such as fosfomycin.
  • Chemical Analysis: It can be used as a reference substance for acid - volume titration to standardize the titration solution.
  • Other Aspects: It is an intermediate for the preparation of surfactants and vulcanization accelerators, and can also be used as an emulsifier for cosmetics (creams, lotions), mineral oils, and paraffins.
• Storage Conditions
  • Store in a cool, dry, and well - ventilated place, away from moisture and heat.
  • Keep away from fire sources, heat sources, and strong oxidants to prevent the occurrence of combustion or explosion hazards.
  • Generally, the shelf - life of the product is about 2 years, and the specific shelf - life can refer to the product manual.
• Safety Information
  • It is a combustible solid, so pay attention to fire prevention during storage and use.
  • Although it has low toxicity, during use, avoid inhaling dust or direct contact with skin and eyes. In case of accidental contact, immediately rinse with a large amount of water and seek medical help.