2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride

Basic information

  • Product Name:2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
  • CasNo.:1185-53-1
  • MF:C4H12ClNO3
  • MW:

Physical and Chemical Properties

  • Purity:99%
  • Boiling Point:
  • Packing:White crystal
  • Throughput:
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Product Details

CasNo: 1185-53-1

MF: C4H12ClNO3

Appearance: White crystal

Delivery Time: 15 days

Packing: 25kg/bag

Purity: 99%

  • Basic Information
    • CAS No.:1185 - 53 - 1
    • Molecular Formula:C₄H₁₁NO₃·HCl
    • Linear Molecular Formula:NH₂C(CH₂OH)₃·HCl
    • Molecular Weight:157.60
    • English Name:Tri(hydroxymethyl)aminomethane hydrochloride
    • English Aliases:Tris(hydroxymethyl)aminoethane hydrochloride, etc.
    • Purity:Usually ≥99.0%, and the ultra - pure grade can be ≥99.5%.
  • Physical and Chemical Properties
    • Appearance:White crystalline powder or acicular crystals.
    • Melting Point:149 - 152℃
    • Boiling Point:219 - 220℃
    • Density:1.28 g/cm³ at 20.2℃
    • Solubility:It is highly soluble in water, slightly soluble in methanol, and hardly soluble in ethanol. The solubility in water is about 561g/L at 25℃.
    • Acidity Coefficient (pKa):8.1
    • pH Value:The pH of a 0.1M aqueous solution is 4.2 - 4.9 at 25℃.
  • Applications
    • It is widely used as a solvent for nucleic acids and proteins, and is one of the main components of protein electrophoresis buffer solutions. Together with glycine, it constitutes a buffer system to stabilize the pH during the electrophoresis process.
    • It is used for protein crystal growth under different pH conditions.
    • Its low - ionic - strength characteristic can be used for the formation of intermediate filaments of lamin in Caenorhabditis elegans.
    • It is also an intermediate for the preparation of surfactants, vulcanization accelerators, and some drugs, and can be used as a titration standard.
  • Storage Method:Seal and store in a cool, dry place. It can be transported and stored at room temperature, and the shelf - life is usually 2 years or more, subject to the product instruction manual.