Product Details
CasNo： 9003-39-8
MF： C6H9NO
Appearance： powder
Delivery Time： 15 days
Packing： 25kg/drum
Purity： 99%
1. Basic Information
(C6H9NO)n
- Molecular Weight: 1000000 - 1500000
- CAS Number: 9003 - 39 - 8
- Synonyms: Polyvinylpyrrolidone; Poly N - vinyl butyrolactam; 1 - Vinyl - 2 - pyrrolidinone homopolymer
- Appearance: Usually appears as a white powder, or it can also be in the form of particles or flaky sheets. It is odorless or has a slightly characteristic odor and is hygroscopic.
- Solubility: It is highly soluble in a variety of solvents such as water, alcohols, amines, and halogenated hydrocarbons. However, it is insoluble in acetone and ether.
2. Quality Standards
- K - value: The K - value should be in the range of 81.0 - 97.2. The K - value is an important parameter that reflects the relative viscosity of the polymer in an aqueous solution and is related to the molecular weight and performance of the product.
- pH Value: The pH value of its aqueous solution should be 4.0 - 7.0, which indicates its stability in a certain pH range and is suitable for use in various formulations that require a specific pH environment.
- Solution Clarity and Color: When 1.0 g of the product is dissolved in 20 ml of water, the resulting solution should be clear and colorless. If it shows turbidity, it should not be more turbid than the No. 1 turbidity standard solution; if it shows color, it should not be deeper than the Yellow No. 1 or Reddish - brown No. 2 standard color - comparison solution. This requirement ensures the visual quality and purity of the product in solution.
- Nitrogen Content: Calculated on an anhydrous basis, the nitrogen content should be 11.5% - 12.8%. Nitrogen content is an important index to measure the purity and quality of Povidone K90 as it is directly related to the molecular structure and composition of the polymer.
3. Category
It is a pharmaceutical excipient and is often used as a binder, thickener, and in other applications.
4. Storage Method
It should be stored at room temperature, avoiding exposure to heat, moisture, and direct sunlight. Under proper storage conditions, the shelf - life is at least 24 months. This storage method helps to maintain the stability and quality of the product, preventing issues such as degradation due to environmental factors.
5. Main Applications
- Efficient Binder: It is widely used in tablets, capsules, and granules as a highly effective binder. For example, in tablet manufacturing, whether through wet granulation, dry granulation, or direct compression processes, Povidone K90 can effectively bind drug powders together, resulting in tablets with high hardness and good integrity, reducing the risk of tablet friability.
- Stabilizer in Suspensions: In oral and topical suspensions, it acts as a stabilizer. It can prevent the sedimentation of drug particles by increasing the viscosity of the dispersion medium and improving the physical stability of the suspension, ensuring uniform drug distribution and consistent dosage during use.
- Solubility Enhancement: It can be used in solid - dispersion formulations to enhance the solubility of poorly soluble active pharmaceutical ingredients. By forming a complex with the drug, it can increase the surface area of the drug in the formulation, promoting its dissolution in the gastrointestinal tract and improving bioavailability.
- Hair Styling Products: Due to its excellent film - forming and high - viscosity properties, it is very suitable for hair - styling products such as hairsprays and hair waxes. When used in hairsprays, it can form a thin, flexible film on the hair surface, providing strong hold to keep the hair in the desired style for an extended period.
- Facial Masks: In facial masks, it serves as a thickener and film - forming agent. As a thickener, it adjusts the viscosity of the mask formula, making it easier to apply and adhere to the skin. As a film - forming agent, it helps to form a continuous film on the skin surface during the drying process of the mask, facilitating the penetration of active ingredients into the skin and improving the overall efficacy of the mask.
- Printing Inks, Paints, and Coatings: It can be applied in printing inks, paints, and coatings. In these products, it functions as a thickener, which helps to adjust the viscosity of the formulation, ensuring proper flow and leveling during application. It also contributes to the adhesion of the coating to the substrate, improving the durability and quality of the final product.
- Adhesives: Povidone K90 can be used as an ingredient in adhesives. Its adhesive properties enable it to bond different materials together, and its solubility and film - forming ability can enhance the performance and stability of the adhesive system.
