Beta-cyclodextrin

Product Details

CasNo： 7585-39-9

MF： C42H70O35

Appearance： powder

Delivery Time： 15 days

Packing： 25kg/bag

Purity： 99%

Basic Information

Product Description

Product Name：Betadex

CAS No: 7585-39-9

Form: Powder

Product Application

1. Solubility & Bioavailability Enhancer (Primary Function):

Acts as a supramolecular host​ by forming non-covalent inclusion complexes with poorly water-soluble drugs (BCS Class II/IV), significantly increasing their apparent solubility in aqueous formulations.

This directly translates to improved oral bioavailability or enables parenteral administration of otherwise insoluble compounds.

2. Stabilizing Agent:

Encapsulates drug molecules, protecting them from hydrolysis, oxidation, or photodegradation, thereby improving shelf-life.

Can prevent drug precipitation upon dilution.

3. Chemical & Physical Modifier:

Taste-Masking:​ Reduces the bitterness and unpleasant taste of APIs in oral formulations.

Reduces Irritation:​ Mitigates local tissue irritation or hemolytic activity of drugs in parenteral and topical products.

Controls Release:​ Can modify the release rate of drugs from formulations.

4. Key Application Areas:

Injectable Formulations:​ A critical component for making parenteral solutions of highly insoluble drugs (e.g., voriconazole, ziprasidone, aripiprazole, remdesivir).

Oral Dosage Forms:​ Tablets, capsules, and oral solutions for solubility enhancement and taste-masking.

Ophthalmic & Nasal Preparations:​ Improves solubility and stability in local delivery systems.

Packaging

25Kg/Bag

Storage

Store in a cool, dry, well-ventilated​ place at controlled room temperature. Keep containers tightly closed​ to protect from moisture. For injectable grades, storage conditions are more stringent.