Cellulose microcrystalline

Product Details

CasNo： 9004-34-6

MF： (C6H10O5)n

Appearance： powder

Delivery Time： 15 days

Packing： 20kg/bag

Purity： 99%

• Basic Information
  • Chinese Name: Micro - crystalline Cellulose PH101
  • English Name: Microcrystalline Cellulose PH101
  • English Aliases: Avicel PH101, Celex PH101, Cellulose - gel PH101, etc.
  • CAS Registration: 9004 - 34 - 6
  • Unique Ingredient Identifier (UNII): OP1R32D61U
  • Molecular Formula: (C₆H₁₀O₅)ₙ, n≈220
  • Molecular Weight: ≈36000
• Physicochemical Properties
  • Appearance: White, odorless, tasteless, crystalline powder composed of porous particles.
  • Hygroscopicity: It is hygroscopic, but stable under normal environmental conditions.
  • Solubility: Insoluble in water, dilute acids and most organic solvents, and partially soluble in sodium hydroxide solution.
• Functional Characteristics
  • As a Pharmaceutical Excipient
    • Diluent: It can increase the volume and weight of tablets or capsules, making the drug easy to process and form, and convenient for patients to take.
    • Disintegrant: It can promote the rapid disintegration of tablets in the gastrointestinal tract, so that the drug can be released more quickly and the bio - availability of the drug can be improved.
    • Binder: It has a certain viscosity. In the wet - granulation process, it can bond the drug powder together to form particles with a certain strength, which is helpful for the forming of tablets.
    • Suspending Agent: It can increase the dispersibility and stability of drug particles in the suspension, prevent particle sedimentation, and make the drug evenly distributed in the suspension.
    • Adsorbent: It can adsorb impurities or odors in the drug, improve the purity and quality of the drug.
  • As a Food Additive
    • Thickener: It can increase the viscosity of food, improve the taste and texture of food, and is applied in foods such as ice cream, yogurt, and jam.
    • Stabilizer: It helps to maintain the stability of food, prevent food from delamination, sedimentation and other phenomena during storage and transportation, and prolong the shelf - life of food.
    • Source of Dietary Fiber: It provides dietary fiber for the human body, helps to promote intestinal peristalsis, and prevents intestinal diseases such as constipation.
• Application Fields
  • Pharmaceutical Industry: Widely used in the production of oral tablets and capsules, such as antibiotics, antiviral drugs, and drugs for treating metabolic system diseases. At present, 70% of the prescriptions that have passed the consistency evaluation use micro - crystalline cellulose as a filler and direct - compression material.
  • Food Industry: Used in the production of frozen foods, cold drinks, desserts, cooking sauces, beverages, pastries and soups. It is also widely used in nutritional and health foods for diabetic patients.
  • Cosmetics Industry: It can be used as a basic raw material of cosmetics, with the functions of filling, thickening and emulsifying. It has a good emulsifying ability for oily substances, and can be used in the manufacture of various cosmetics, skin - care products and cleaning detergents.
• Production Method: It is usually prepared by controlling the hydrolysis of α - cellulose with dilute inorganic acid solution. α - cellulose can be obtained from the fiber pulp of cellulose - containing plants. After hydrolysis, the hydrolyzed cellulose is filtered, purified, and the water slurry is spray - dried to form dry, porous particles with a wide particle size distribution.
• Safety Information
  • This product is widely used in oral pharmaceutical preparations and foods. It is a relatively non - toxic and non - irritating substance. It is not absorbed after oral administration and has almost no potential toxicity.
  • Large - scale use may cause mild diarrhea.
  • The abuse of certain tablets containing cellulose, such as inhalation or injection, will lead to cellulose granuloma.