Croscarmellose sodium

Product Details

CasNo： 74811-65-7

MF： C28H36O26Na4

Appearance： powder

Delivery Time： 15 days

Packing： 25kg/bag

Purity： 99%

Basic Information

Product Description

Product Name：Croscarmellose Sodium

CAS No: 74811-65-7

Form: Powder

Product Application

Croscarmellose Sodium is used exclusively as a super-disintegrant​ in oral solid dosage forms. Its main purpose is to facilitate the rapid breakup of tablets and capsules in the gastrointestinal fluid, thereby increasing the surface area of the drug and enhancing its dissolution and bioavailability.

Formulations:​ Tablets, capsules (including capsule plugs), and granules.

Process Compatibility:​ Effective in both direct compression​ and wet granulation​ processes.

Intragranular Addition:​ Added to the powder blend before granulation for controlled disintegration.

Extragranular Addition:​ Added to the dry granules before final compression (most common method for fastest disintegration).

Typical Use Concentration:​ 0.5% - 5.0% (w/w), with 2% - 3% being common for immediate-release tablets.

Packaging

25Kg/Drum

Storage

Store in a tightly closed container in a cool, dry place (≤ 25°C). Protect from moisture to prevent loss of disintegrant efficacy.