Isopropyl myristate

Product Details

CasNo： 110-27-0

MF： C17H34O2

Appearance： liquid

Delivery Time： 15 days

Packing： 200kg/drum

Purity： 99%

1. Basic Information

• Chemical Name: Isopropyl myristate
• Synonyms: Tetradecanoic acid 1 - methylethyl ester; Propan - 2 - yl tetradecanoate
• Chemical Formula: C17​H34​O2​
• Molecular Weight: 270.45 g/mol
• CAS Number: 110 - 27 - 0

2. Physical and Chemical Properties

• Appearance: It presents as a colorless, transparent, oily liquid at room temperature. It is odorless or has a very faint, almost imperceptible odor.
• Solubility: Insoluble in water. However, it is miscible with a wide range of organic solvents, such as ethanol, ether, methylene chloride, and various natural and synthetic oils. This solubility property makes it highly adaptable in different formulation systems.
• Density: Approximately 0.864g/cm3 at 25∘C. Density is an important physical parameter, which affects its blending ratio in formulations and the overall physical characteristics of the final product.
• Boiling Point: Boils at around 319.9∘C at 760 mmHg. But it should be noted that at high temperatures, there may be a risk of decomposition or oxidation in the presence of air.
• Flash Point: The flash point is about 144.1∘C, indicating its relatively low flammability under normal conditions.
• Vapor Pressure: The vapor pressure at 25∘C is 0.000329mmHg, suggesting that it has a very low volatility at room temperature.
• Refractive Index: The refractive index (nD20​) ranges from 1.434 - 1.437, which is useful for quality control and identification in industrial applications.
• Specific Gravity: The specific gravity (d420​) is in the range of 0.850 - 0.855, which is another characteristic property for product specification and quality assessment.

3. Quality Standards

• Ester Content: The minimum ester content should be ≥ 98%. High - purity isopropyl myristate is crucial for its performance in various applications. Advanced analytical techniques, such as gas chromatography (GC), are often used to accurately measure the ester content.
• Acidity: The acidity, expressed as mg KOH/g, should be ≤ 0.5. This parameter is important as excessive acidity can affect the stability of products in which it is incorporated, especially in sensitive formulations like cosmetics and pharmaceuticals. Titration methods are commonly employed to determine the acidity.
• Heavy Metals: The content of heavy metals, with lead (Pb) as the main indicator, should be ≤ 5 ppm. Stringent control of heavy metals is essential to meet the safety requirements of products, especially those in contact with human skin or for oral use. Atomic absorption spectrometry (AAS) or inductively coupled plasma - mass spectrometry (ICP - MS) are used for heavy metal analysis.
• Arsenic (As): The arsenic content should be ≤ 2 ppm. Similar to heavy metals, arsenic is a toxic element, and its low - level presence is closely monitored using highly sensitive analytical methods like ICP - MS.

4. Applications

• Cosmetics Industry:
  • Skin - Care Products: It is widely used in creams, lotions, serums, and facial masks. Its excellent skin - penetration ability allows other active ingredients in the formulation to be better absorbed by the skin. For example, in anti - aging creams, it helps carry retinol or hyaluronic acid deeper into the skin layers, enhancing their effectiveness. It also provides a smooth, non - greasy feel, improving the texture of the product.
  • Makeup Products: In lipsticks, foundations, and eyeshadows, isopropyl myristate acts as a binder and emollient. It helps blend pigments evenly, resulting in a more uniform color distribution. In lipsticks, it gives a creamy texture and improves the durability of the color on the lips.
  • Hair - Care Products: Added to shampoos, conditioners, and hair styling products, it helps to moisturize the hair, reduce frizz, and improve manageability. It can also enhance the shine of the hair, making it more aesthetically appealing.
• Pharmaceutical Industry:
  • Topical Preparations: It is used in ointments, creams, and gels for its emollient and penetration - enhancing properties. For example, in topical anti - inflammatory medications, it helps the active drug ingredient to penetrate the skin more effectively, reaching the target tissue faster and improving the therapeutic effect.
  • Oral Medications (rarely): In some cases, it may be used as a non - toxic solvent or vehicle in certain oral liquid formulations, although its use in oral medications is relatively less common compared to topical applications.
• Other Industrial Applications:
  • Lubricants: Due to its oily nature and low volatility, it can be used as a component in some specialized lubricants, especially those designed for applications where a non - reactive, long - lasting lubricating film is required.
  • Plasticizers: In the plastics industry, it can function as a plasticizer in some polymer systems, improving the flexibility and processability of plastics.

5. Safety Information

• Toxicology: Generally regarded as a low - toxicity substance. Acute toxicity studies have shown that it has a relatively high LD50 (lethal dose 50, the dose at which 50% of test animals die). In animal experiments, oral LD50 values are often in the range of several grams per kilogram of body weight. However, like any chemical, over - exposure or inappropriate use may pose risks.
• Skin Sensitization: Although it is not a common skin sensitizer, in some individuals with sensitive skin, it may cause mild irritation or allergic reactions. Patch tests are often recommended for new product formulations containing isopropyl myristate to assess potential skin - related issues.
• Environmental Impact: It is relatively biodegradable. In the environment, it can be broken down by microorganisms over time. However, like all chemicals, large - scale releases into water bodies or soil should be avoided to prevent any potential negative impacts on aquatic or terrestrial ecosystems.

6. Storage and Handling

• Storage: Store in a cool, dry, well - ventilated area away from direct sunlight and heat sources. The recommended storage temperature is between 5 - 25°C. It should be kept in tightly - sealed containers to prevent oxidation and contamination. Under proper storage conditions, its shelf life is typically 2 - 3 years.
• Handling: When handling isopropyl myristate, standard safety precautions should be taken. Wear appropriate personal protective equipment, such as gloves and safety glasses, to avoid direct skin and eye contact. In case of contact with skin, wash thoroughly with soap and water. If it gets into the eyes, rinse immediately with plenty of water and seek medical attention.