Appearance: White crystalline powder or colorless prismatic crystals
Density: 1.58g/m³ (25℃)
Melting Point: 152℃ - 156℃
Boiling Point: 323℃ (at normal pressure)
Solubility: Easily soluble in water, alcohol, and acetone; slightly soluble in ether, ethyl acetate, chloroform, and pyridine; insoluble in benzene.
Stability: Sensitive to light and heat, easily oxidized in the air, and can chelate with many metal ions.
Synthesis Method
Industrially, it is usually prepared by the fermentation of Aspergillus (including Aspergillus oryzae, Aspergillus flavus, etc.) with starch or molasses as raw materials, followed by refining.
Quality Indicators
Appearance: Off - white needle - like crystals or powder
Purity: ≥99.0%
Loss on Drying: <0.5%
Residue on Ignition: <0.5%
Iron Content: <10ppm
Heavy Metals: <3ppm
Arsenic Content: <1ppm
Chloride Content: <50ppm
Application Fields
Cosmetics Field: It can inhibit the synthesis of tyrosinase and strongly inhibit the formation of skin melanin. It can be formulated into lotions, masks, emulsions, etc., and is used to treat freckles, age spots, etc. The general addition amount is 0.5% - 2.0%.
Food Processing Field: It can be used as a food additive to play the roles of preservation, anti - corrosion, and anti - oxidation, and can also inhibit the conversion of sodium nitrite to nitrosamine in smoked meat.
Pharmaceutical Field: It can be used as a raw material for cephalosporin - class antibiotics, and is used to treat diseases such as headaches, toothaches, and local inflammations, with ideal analgesic and anti - inflammatory effects.
Agricultural Field: It can be used to produce biological pesticides. The biological micro - fertilizer made by adding 0.5% - 1.0% kojic acid has an obvious yield - increasing effect on grains and vegetables.
Other Fields: It can also be used as an iron analysis reagent, a film spot remover, etc.
Precautions
Kojic acid is unstable to light, heat, and metal ions. Do not add it at high temperature during formulation, and control the content of metal ions such as iron in the system. It is better to add appropriate complexing agents such as EDTA and antioxidants such as sodium sulfite in the system.