Basic Information: The English name is Deoxyarbutin, with the CAS number 53936 - 56 - 4. The molecular formula is C₁₁H₁₄O₃, and the molecular weight is 194.23. The alias is 4 - ((Tetrahydro - 2H - pyran - 2 - yl)oxy)phenol.
Physical and Chemical Properties: It is a white or off - white powder. It is insoluble in water, soluble in methanol, ethanol, DMSO and other organic solvents, and the melting point is 86 - 87℃. It has excellent thermal and photostability.
Whitening Efficacy: It is a highly effective whitening active ingredient, a reversible tyrosinase inhibitor, which can regulate melanin production. Its inhibitory effect on tyrosinase is significantly better than other whitening agents. The IC50 value of inhibiting tyrosinase activity can reach 50 nM, and its effectiveness is 10 times that of hydroquinone, 150 times that of kojic acid, and 350 times that of common arbutin.
Application Fields: Mainly used in high - end whitening cosmetics, such as facial creams, lotions, essences, etc. The recommended addition amount in cosmetics is 0.1% - 3%.
Packaging Specifications: Usually packaged in 1 - kg aluminum foil bags, 5 - kg cardboard drums, 25 - kg cardboard drums, etc., and can also be customized according to customer needs.
Storage Method: It needs to be stored in a sealed, low - temperature, dry and light - proof place, and should be kept away from strong acids and strong alkalis.
Kojic Acid
Basic Information: The English name is Kojic Acid, and the chemical name is 5 - Hydroxy - 2 - (hydroxymethyl)-1,4 - pyranone. The molecular formula is C₆H₆O₄, and the molecular weight is 142.11.
Physical and Chemical Properties: It is a white crystalline powder, with a melting point of 152.0 - 156.0℃. It is easily soluble in water and ethanol, insoluble in oils, sensitive to light and heat, and easily oxidized in the air. It can chelate with many metal ions.
Whitening Efficacy: It can inhibit the synthesis of tyrosinase and strongly inhibit the formation of skin melanin, with a significant whitening effect. The activity of various tyrosinases can be inhibited by 70% - 80% at a concentration of 20μg/ml.
Application Fields: Widely used in whitening and sunscreen cosmetics, such as toners, masks, lotions, etc. The general addition amount in cosmetics is 0.5% - 2.0%. In addition, it can also be used as a preservative, fresh - keeping agent and color - protecting agent in food, and can also be used in the pharmaceutical field to produce cephalosporin - class antibiotics, as well as in the production of biological pesticides.
Synthesis Method: Industrially, it is usually prepared by the fermentation of Aspergillus microorganisms using starch or molasses as raw materials, followed by refining.
Storage Method: It should be stored in a sealed package, away from high temperature and high humidity.