Chinese Name: Trimethyl orthoformate, also known as trimethoxymethane.
English Name: Trimethyl orthoformate or Trimethoxymethane.
CAS No.: 149 - 73 - 5.
Molecular Formula: C₄H₁₀O₃.
Molecular Weight: 106.12.
EINECS: 205 - 745 - 7.
Physical and Chemical Properties
Appearance: Colorless transparent liquid with an ester - like odor.
Boiling Point: 101 - 102 °C.
Relative Density: 0.97 g/mL at 25 °C.
Refractive Index: 1.379 (20 °C).
Flash Point: 60 °F (about 15.6 °C).
Melting Point: - 53 °C.
Vapor Pressure: 23.5 mm Hg (20 °C).
Solubility: Miscible with ether, alcohol and benzene.
Explosion Limit: 1.4 - 44.6% (V).
Chemical Properties6
It will decompose rapidly when encountering water, generating methanol and methyl formate. The reaction equation is HC(OCH₃)₃ + H₂O→HCOOCH₃ + 2CH₃OH.
It can react with both acids and bases, so it should be kept away from acids and bases during storage and use.
It can participate in various organic chemical reactions such as trans - esterification reaction and condensation reaction, and is an important organic synthesis intermediate.
Uses5
Pharmaceutical Field: It is an important intermediate for the synthesis of drugs such as vitamin B1, vitamin A, sulfadiazine, pipemidic acid and antibacterial agents.
Coating Field: It is used as a dehydrating agent to prevent the hardening of polyurethane or epoxy coatings due to hydration, improving the performance of coatings.
Fragrance and Pesticide Fields: As a raw material, it is used in the synthesis of fragrances and pesticides, providing specific odors for products or enhancing their chemical properties.
Quality Standards
The content of trimethyl orthoformate is usually ≥99%.
The content of methanol is ≤0.3%.
The content of methyl formate is ≤0.2%.
The content of other impurities is ≤0.05%.
Packaging and Storage
Packaging: Usually packed in 200 - kg galvanized iron drums or glass bottles, which are reinforced with wooden cases or calcium - plastic cases and lined with cushioning materials.
Storage Conditions: It should be stored in a dry, ventilated and moisture - proof warehouse. It is strictly prohibited to stack outdoors or in high - temperature areas. Keep away from fire sources and strictly prevent contact with water. During transportation, ensure that the container does not leak, collapse, fall or be damaged, and prevent sun exposure and rain.