Defoamer DF-104

Product Details

CasNo： 9003-11-6

MF： HO.(C2H4O)m.(C3H6O)n.H

Appearance： liquid

Delivery Time： 15 days

Packing： 200kg/drum

Purity： 99%

I. Basic Information

(1) Product Name

DF - 104 High - Temperature Fermentation Defoamer

(2) Packaging Specification

210 kilograms per blue iron barrel. This kind of packaging is sturdy and durable, which can effectively prevent product leakage, volatilization or contamination during transportation and storage, and is convenient for handling and storage in large - scale industrial use scenarios.

(3) Main Ingredient

Polyether. It is produced by ring - opening polymerization of monomers such as ethylene oxide and propylene oxide under the action of catalysts. The monomer ratio and polymerization method can be adjusted according to different fermentation process requirements to obtain a polyether molecular structure with specific properties.

II. Product Characteristics

(1) Appearance and Physical Properties

It is usually a colorless to light yellow transparent or translucent liquid, with uniform texture and good fluidity. It has an appropriate viscosity, which ensures that it can be quickly dispersed in the fermentation system during use and avoids affecting the defoaming durability due to excessively low viscosity; the density is between 0.9 - 1.1 g/cm³, and the flash point is relatively high, so it is safe in the industrial use environment.

(2) Core Performance Advantages

1. Excellent High - Temperature Resistance: Designed specifically for high - temperature fermentation environments, it can stably perform defoaming and foam - inhibiting functions in the high - temperature range of 60 - 120°C. Under high - temperature conditions, the molecular structure is stable, without decomposition or volatilization, and continuously and effectively controls foam to ensure the smooth progress of the fermentation process.
2. Efficient Defoaming and Foam Inhibition: It can quickly penetrate the foam film, reduce the surface tension, and make the foam burst rapidly; at the same time, it forms a durable protective film on the surface of the fermentation broth, effectively inhibiting the formation of new foam. Even in the stage of vigorous fermentation and large amount of foam generation, it can respond quickly and control the foam volume at a very low level.
3. Good Biocompatibility: It will not have a negative impact on the growth and metabolism of fermenting microorganisms. It can coexist well with fermentation systems such as bacteria, fungi and actinomycetes, without interfering with the normal physiological activities of microorganisms, and ensuring the yield and quality of fermentation products.
4. High Chemical Stability: It has excellent tolerance to common chemical substances such as acids, alkalis and salts in the fermentation process, and does not chemically react with fermentation raw materials, intermediate products and final products, ensuring that the purity of fermentation products is not affected and meeting the strict quality requirements of food, pharmaceutical and other industries.

III. Action Principle

With its special structure, polyether molecules quickly migrate to the gas - liquid interface, significantly reducing the surface tension of the fermentation broth. When foam is formed, polyether molecules insert into the foam liquid film, destroying the elasticity and stability of the film and causing the foam to burst. At the same time, the polyether molecules dispersed in the fermentation broth continue to play a role, preventing the aggregation and fusion of bubbles and inhibiting the regeneration of foam, thus achieving the dual effects of defoaming and foam inhibition.

IV. Applicable Fields

(1) Monosodium Glutamate (Glutamic Acid) Fermentation

In the process of producing monosodium glutamate by fermentation of Corynebacterium glutamicum, it can effectively eliminate a large number of foams generated by aeration and stirring, and nutrient metabolism. It maintains a good gas - liquid mass transfer environment in the fermentation tank, ensures sufficient dissolved oxygen, promotes the efficient synthesis of glutamic acid, and improves the yield and quality of monosodium glutamate.

(2) Enzyme Preparation Fermentation

Suitable for the fermentation of various enzyme preparations such as amylase, protease and lipase. Controlling foam can avoid the risk of fermentation liquid overflow and contamination, maintain a stable fermentation environment, and promote the efficient expression of target enzymes by microorganisms, thereby improving the activity and yield of enzyme preparations.

(3) Biopharmaceutical Fermentation

Indispensable in the fermentation production of antibiotics such as erythromycin, oxytetracycline and penicillin. It prevents problems such as unstable fermentation system and contamination caused by foam, ensures the continuous and stable progress of the antibiotic fermentation process, and helps the large - scale industrial production of high - quality drugs.

(4) Citric Acid Fermentation

When Aspergillus niger is used to produce citric acid by fermentation, it eliminates foam in time to ensure the effective use of space in the fermentation tank, optimize fermentation parameters, improve the yield of citric acid and reduce production costs.

(5) Other Amino Acid Fermentation

In the fermentation process of amino acids such as lysine and threonine, it effectively controls foam, creates a good condition for the growth and metabolism of microorganisms, and improves the yield and purity of amino acids.

V. Usage Methods and Precautions

(1) Usage Methods

1. Timing of Addition: It can be added as a basic addition before the start of fermentation, or it can be added in real time according to the foam generation during the fermentation process. It is recommended to add a small amount in the early stage of fermentation to inhibit the formation of initial foam; in the middle and late stages of fermentation, according to the changing trend of foam, the continuous dripping or intermittent addition method is adopted to control the foam.
2. Amount of Addition: Generally, the addition amount is 0.01% - 0.1% of the total volume of the fermentation broth. The specific dosage needs to be determined through small - scale tests according to the actual conditions such as fermentation strains, fermentation processes and fermentation equipment to achieve the balance between the best defoaming effect and cost control.
3. Method of Addition: A metering pump is used to precisely control the flow rate, and the defoamer is evenly and slowly added into the fermentation tank. It can also be diluted 5 - 10 times with sterile water before adding to promote its rapid dispersion in the fermentation broth.

(2) Precautions

1. Storage Conditions: Store in a cool, dry and well - ventilated warehouse, avoid direct sunlight and high - temperature environment, and keep away from fire sources and strong oxidants. The storage temperature is recommended to be controlled at 5 - 35°C to prevent the product from deteriorating due to excessively high temperature and affecting the use effect.
2. Compatibility Contraindications: Before using it in combination with other fermentation additives, a compatibility test must be carried out. Avoid direct contact with strong acids, strong alkalis, strong oxidants and other substances to prevent chemical reactions and reduce the performance of the defoamer.
3. Safety Protection: It is recommended to wear protective gloves, goggles and other protective equipment during operation. If it accidentally comes into contact with the skin or eyes, rinse immediately with plenty of water and seek medical treatment in time.